Research Participation Opportunities for our People

Last Updated: 2021-01-12

Sinai Health is an academic health sciences centre, fully affiliated with the University of Toronto. As part of the Toronto Academic Health Science Network, our mandate is to lead in providing safe, high quality care, accelerating discoveries, finding solutions and applying innovations.

While the COVID-19 pandemic continues to evolve, researchers at Sinai Health are looking to understand the pandemic and the virus, including its impact on health care workers.

Below are some current research opportunities that Sinai Health’s people (employees, physicians, scientists, learners and volunteers) may be interested in participating in. These studies have been the Research Ethics Board approved.

Risk factors for COVID-19 in hospital workers

Investigators: Dr. Allison McGeer & Dr. Brenda Coleman

What is being studied?

  • The number of COVID-19 infections and factors linked with infection
  • Antibodies against COVID-19
  • Effect of COVID-19 vaccines
  • Psychological impact of working during a pandemic

Who are they looking for?
Staff working in participating acute care, rehabilitation, or complex care hospitals

  • Who are 18-75 years of age
  • Who work 20 hours or more per week – or – physicians/nurse practitioners who care for patients for 8 hours or more per week
  • Who has a home computer or phone with internet access
  • Plans to be available for the next 3 months

What is required?

  • Questionnaires when you join and then every week (online)
  • Report when you are tested for COVID-19 and submit a swab to the study the same day
  • Report when you are vaccinated against COVID-19
  • Blood samples: provide none, one, or several (optional)
  • Invite adults and children in your home to join (optional)

*Participation is voluntary.

Participants will be provided with a small token of appreciation for taking part in the study

For further information visit here or email [email protected]

HealthyHCW Study

Investigator: Dr. Keith Jarvi, Co-investigators: Dr. Anne-Claude Gingras and Dr. Jennifer Taher

We invite you to be a part of a study at the Mount Sinai Hospital to help us understand how many hospital workers have been infected with COVID-19 and if age, health or type of work changes your risks of being infected with COVID-19 and risks of having more severe COVID-19. You are invited to take part if you have no current symptoms of COVID-19, and, if previously infected, have completely recovered from the infection. We would also like to monitor you for up to 18 months to see if you become infected with COVID-19 in the future.

Infections with COVID-19 cause a variety of symptoms, from very severe breathing problems potentially needing a ventilator to infections causing no or very minimal symptoms. Even if you have not had symptoms of COVID-19, it is possible that you have been infected with COVID-19. A blood test can be used to find out if you have been infected in the past with COVID-19.

Volunteers will complete a de-identified questionnaire and provide a small blood sample from the tip of a finger. You will be given the results of the tests to know if you have had a previous infection with COVID-19. You will have to repeat testing at 3, 6, 12 and 18 months to find out if you have a new COVID-19 infection. Each visit should take less than 20 minutes.

If you are interested, e-mail [email protected] or call (416) 584-4800 x5375 for more details.

CONCOR-1 Clinical Trial

Investigators: Drs. Michael Fralick & Nadine Shehata

The CONCOR-1 study is a Canadian randomized controlled trial comparing convalescent plasma vs no plasma for patients with a COVID-19 respiratory illness. Thank you to individuals who have donated plasma following recovery from an illness due to COVID-19 in the past.

If you, your family member or friend have recovered from COVID -19, please consider donating plasma after recovery. You can determine your eligibility by visiting https://blood.ca/en/convalescentplasma

SHAWL-1 (Stay-Healthy-At-Work) Study

Investigators: Dr. Pamela Goodwin, Dr. Anne-Claude Gingras, Dr. Rod Bremner, Dr. Jeff Wrana, Dr. Jim Woodgett, Dr. Rita Kandel, Dr. Tony Mazzulli, Dr. Keith Jarvi, Dr. Steven Gallinger

The SHAWL-1 study is looking for research participants who 1) work at, or have a relationship with, LTRI/Sinai Health or OICR and 2) are healthy with no current symptoms of COVID-19 or have been cleared by Occ Health to return to work.

Study Goals:

  1. To develop safe and efficient testing protocols for the simultaneous profiling of SARS-CoV-2 antibodies and viral RNAs using self-sampling collection protocols.
  2. To use systematic testing of employees of the LTRI/Sinai Health or OICR for both antibodies and viral RNAs to survey the prevalence of COVID-19 related disease (antibodies and acute illness) in an asymptomatic population.

If you are interested, contact [email protected]