Dr. Adele Changoor

PhD
Translational Research Scientist

Department of Surgery (Orthopaedics), Mount Sinai Hospital

Engineering better diagnostics and therapies for joint disease and musculoskeletal health

Our aim is to develop better tools and therapies to address joint disease, so people can move and live with less pain. Our multidisciplinary research is focused on orthopaedics and arthritis, with collaborators spanning bioengineering, orthopaedic surgery, veterinary medicine, biology, kinesiology, sports medicine and rheumatology. 

We integrate engineering principles with clinical applications to address challenges in musculoskeletal health, which encompasses the health of the muscles, bones, joints, tendons and ligaments that provide support and allow movement. 

Key areas of interest include:

  1. The development of electroarthrography, a non-invasive method to assess cartilage quality for diagnosing conditions like arthritis.
     
  2. Innovations in osteochondral allograft transplantation, which is a surgical repair technique for treating cartilage defects.
     
  3. Studying pelvic biomechanics to inform surgical decision-making in complex hip replacement surgeries. 
Telephone
Contact

Email: [email protected]

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Location

Room 415, 25 Orde Street 
Toronto, M5T 3H7

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Related links

Publications: Pubmed
ORCID: 0000-0002-0175-6227
LinkedIn: Adele Changoor
 

Accordion Items
  • 2025–present; Translational Research Scientist, Lunenfeld-Tanenbaum Research Institute, Sinai Health, Toronto
  • 2025–present; Assistant Professor, Institute of Biomedical Engineering, University of Toronto, Toronto
  • 2024–present; President, Canadian Connective Tissue Society, Toronto  
  • 2024–present; Committee Member, Division of Orthopaedic Surgery Research Committee, Department of Surgery, University of Toronto, Toronto
  • 2023–present; Committee Member, Wellness, Inclusion, Diversity and Inclusion (WIDE) Committee, Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto
  • 2021–present; Assistant Professor, Department of Materials Science & Engineering, University of Toronto, Toronto
  • 2020–present; Assistant Professor, Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto
  • 2019–present; Assistant Professor, Faculty of Medicine and Faculty of Applied Science & Engineering, University of Toronto, Toronto
  • 2019–present; Assistant Professor, Department of Surgery, University of Toronto, Toronto

Former appointments

  • 2019–2025; Staff Scientist, Lunenfeld-Tanenbaum Research Institute, Sinai Health, Toronto
  • 2015–2019; Research Associate, Laboratory of Dr. Marc Grynpas, Lunenfeld-Tanenbaum Research Institute, Sinai Health, Toronto
  • PhD, Biomedical Engineering, École Polytechnique Montréal, Canada; 2011
  • MSc, Biomedical Engineering, University of Guelph, Canada; 2004  
  • BSc (Eng.) Biological Engineering Co-op, University of Guelph, Canada; 2002 
  • 2014 – Top Presentation in Biological Repair & Tissue Regeneration Category (Podium Presentation), 2014 Bone and Joint, Injury and Repair Conference, London, Canada
  • 2011 – Natural Sciences and Engineering Research Council of Canada (NSERC) Postdoctoral Fellowship
  • 2010 – ICRS Certificate of Achievement Cum Laude (Podium Presentation), 2010 World Congress of the International Cartilage Repair Society (ICRS), Sitges, Spain
  • 2009 – ICRS Certificate of Merit (Scientific Poster Presentation), 2009 World Congress of the International Cartilage Repair Society (ICRS), Miami, USA
  • 2005 – Natural Sciences and Engineering Research Council of Canada (NSERC) Post Graduate Scholarship 

Notable publications

Patient-specific 3D-printed drill guides for an ovine osteochondral allograft transplantation model

Journal of Orthopaedic Research, 2025

Non-invasive electroarthrography measures cartilage in live horses and correlates to direct measurements of cartilage streaming potentials in weight bearing regions of equine metacarpophalangeal joints

Osteoarthritis and Cartilage, 2024

Irregular porous titanium enhances implant stability and bone ingrowth in an intra-articular ovine model

Journal of Orthopaedic Research, 2022

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